HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 41390733, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | ethyl 2-{[(2-nitrophenyl)carbonyl]amino}benzoate | HCID 710775 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 41390733 | HCID 41390733 | — |
Reaction Steps
Nitro compound 20 (2.24 g, 7.14 mmol) and Pd/C (220 mg) was dissolved in EtOAc (50 mL) and MeOH (20 mL) and stirred vigorously under H2 atmosphere (1 atm). After 5 h, the Pd/C was filtered off over a pad of celite and florisil to leave pure aniline compound 21 in quant. yield (1.98 g) over two steps.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993622B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-a3b95d8d33ba4ad596faf12f50998144 |
| Source note | uspto-grants-2015_03 |