HCID 178443847, compound → HCID 178484383, compound
Reaction equation
[CH3:1][N:2]([CH3:26])[C:3]([NH:5][C:6](=[NH:25])[NH:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12](C(CCCCCC)C([O-])=O)=[CH:11][CH:10]=1)=[NH:4].CN(C)C(NC(=N)NCC1C=CC(CC[N:43](CC)[C:44](=[O:46])[O-:45])=CC=1)=N>>[C:9]([O:45][C:44](=[O:46])[NH:43][C:12]1[CH:11]=[CH:10][C:9]([CH2:8][NH:7][C:6]([NH:5][C:3](=[NH:4])[N:2]([CH3:1])[CH3:26])=[NH:25])=[CH:14][CH:13]=1)([CH3:14])([CH3:10])[CH3:8]Participants
3
Procedure
In a similar manner 4-{[3-(N,N-Dimethylcarbamimidoyl)guanidino]methyl}phenyl-octanoate (Example 14) and 4-{[3-(N,N Dimethylcarbamimidoyl)guanidino]methyl}phenyl-diethylcarbamate (Example 15) were synthesized.
Sources & evidence
- ORD record
- ord-3b433eb2dbc24a0398270c92dce23861
- Source dataset
- uspto-grants-2015_03
- Patent number
- US08993633B2
Reaction notes
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