Sodium borohydride → HCID 58338939, compound

Participants

Reaction Steps

To a suspension of 4MT-CHO (1.35 g, 3.5 mmol) in 30 mL dry ethanol was added 265 mg (7 mmol) sodium borohydride in small portions. The reaction mixture quickly changed color from orange to yellow and the stirring was continued for 30 min. Removal of the solvent under reduced pressure followed by purification with flash silica gel column chromatography using chloroform as eluent yielded yellow crystals (1.32 g, 97.2%).

Provenance & Evidence