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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 88179Generated: October 25, 2026

2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-[(6-methyl-5-{[2-(3-oxomorpholin-4-yl)ethoxy]methyl}pyridin-2-yl)amino]thiophene-3-carboxamide

https://huagongshe.com/reaction/88179

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Reactant4-{2-[(6-Chloro-2-methylpyridin-3-yl)methoxy]ethyl}morpholin-3-oneHCID 59525966—
Product5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-[(6-methyl-5-{[2-(3-oxomorpholin-4-yl)ethoxy]methyl}pyridin-2-yl)amino]thiophene-3-carboxamideHCID 59525651—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-b7809a5e5b564119ba814883eaead799
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)