(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → Gluconic Acid

Participants

Reaction Steps

Over two hours, 164 g. of 12% active chlorine sodium hypochlorite solution are added, a quantity corresponding with a molar weight 1:1 with respect to the glucose, by maintaining the pH value between 7.0 and 9.0 and, at the end of the addition, the stirring is continued for other 30 minutes. The control of the accomplished execution is carried out through HPLC or through polarimetric readings. The oxidation of glucose to gluconic acid is obtained, as it can be verified by the 13C NMR spectrum depicted in FIG. 1.

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