4-Benzyloxy-2(1H)-pyridone → tert-Butyl 2-(4-(benzyloxy)-2-oxopyridin-1(2H)-yl)-7,9-dimethyl-5,7,8,9-tetrahydro-6H-pyrido[3',4':4,5]pyrrolo[2,3-b]pyridine-6-carboxylate

Participants

Reaction Steps

tert-Butyl 2-bromo-7,9-dimethyl-5,7,8,9-tetrahydro-6H-pyrido[3′,4′:4,5]pyrrolo[2,3-b]pyridine-6-carboxylate (enantiomer B) (100 mg, 0.263 mmol) and 4-(benzyloxy)pyridin-2(1H)-one (53 mg, 0.263 mmol) were reacted following the procedure for Example 2 (step e) to provide the title compound (39 mg, 30%) as a yellow oil: ESI MS m/z 501 [M+H]+.

Provenance & Evidence