反应详情

Selenium dioxyde (1.6 g, 14 mmol, 1.3 eq) in suspension in dioxane (50 mL) was heated at 60° C. 7-bromoquinaldine (2.5 g, 11.2 mmol) was the introduced and the mixture was left to react at 80° C. for 3 hours. After cooling to room temperature, the mixture was filtered on celite, eluted with dioxane and concentrated under reduced pressure. The product was obtained pure as a white solid (3.3 g, >98%).

1. additionintroduced
2. waitthe mixture was left
3. customto react at 80° C. for 3 hours
4. filtrationthe mixture was filtered on celite
5. washeluted with dioxane
6. concentrationconcentrated under reduced pressure