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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 882319Generated: November 1, 2026

Water → HCID 16679760, compound

https://huagongshe.com/reaction/882319

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 11195294HCID 11195294—
SolventAcetonitrileHCID 6342—
ProductHCID 16679760HCID 16679760—

Reaction Steps

First, sodium hydroxide and water were added to 5-tert-butylthiomethyl-5-methylhydantoin, and the resultant mixture was heated to a predetermined temperature and stirred. The reaction solution was analyzed by HPLC (column: COSMOSIL 5C18-AR (produced by Nacalai Tesque Inc.), mobile phase: acetonitrile/10 mM aqueous potassium dihydrogen phosphate solution=30/70, flow rate: 1.0 ml/min, detection wavelength: 210 nm, column temperature: 40° C.) to determine the yield of the title compound. The results are shown in Table 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08993800B2
Source datasetuspto-grants-2015_03
ORD IDord-499bc408083d4f0bb8f13129ae0ba310
Source noteuspto-grants-2015_03