HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 16679760, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 11195294 | HCID 11195294 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 16679760 | HCID 16679760 | — |
Reaction Steps
First, sodium hydroxide and water were added to 5-tert-butylthiomethyl-5-methylhydantoin, and the resultant mixture was heated to a predetermined temperature and stirred. The reaction solution was analyzed by HPLC (column: COSMOSIL 5C18-AR (produced by Nacalai Tesque Inc.), mobile phase: acetonitrile/10 mM aqueous potassium dihydrogen phosphate solution=30/70, flow rate: 1.0 ml/min, detection wavelength: 210 nm, column temperature: 40° C.) to determine the yield of the title compound. The results are shown in Table 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08993800B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-499bc408083d4f0bb8f13129ae0ba310 |
| Source note | uspto-grants-2015_03 |