1-Methyl-4-(piperidin-4-yl)piperazine → 2-(3,4-diethyl-benzyl)-1-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butan-1,4-dione
Reaction equation
[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]([CH2:6][CH:7]([C:8](=[O:9])[OH:10])[CH2:11][C:12]([N:13]2[CH2:14][CH2:15][CH:16]([N:19]3[C:20](=[O:29])[NH:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[CH2:28]3)[CH2:17][CH2:18]2)=[O:30])[cH:31][cH:32][c:33]1[CH2:34][CH3:35].[CH3:36][N:37]1[CH2:38][CH2:39][N:40]([CH:43]2[CH2:44][CH2:45][NH:46][CH2:47][CH2:48]2)[CH2:41][CH2:42]1>>[CH2:1]([CH3:2])[c:3]1[cH:4][c:5]([CH2:6][CH:7]([C:8](=[O:9])[N:46]2[CH2:45][CH2:44][CH:43]([N:40]3[CH2:39][CH2:38][N:37]([CH3:36])[CH2:42][CH2:41]3)[CH2:48][CH2:47]2)[CH2:11][C:12]([N:13]2[CH2:14][CH2:15][CH:16]([N:19]3[C:20](=[O:29])[NH:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]4[CH2:28]3)[CH2:17][CH2:18]2)=[O:30])[cH:31][cH:32][c:33]1[CH2:34][CH3:35]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-fe1f0c3ded82439f89552760c953b3c7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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