Cyclohexane, (bromomethyl)- → 2-Bromo-5-(cyclohexylmethoxy)benzaldehyde

HRID 882466Notes

Reaction equation

HRID 882466 reaction equation
[Br:1][C:2]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][C:3]=1[CH:4]=[O:5].Br[CH2:12][CH:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1>>[Br:1][C:2]1[CH:9]=[CH:8][C:7]([O:10][CH2:12][CH:13]2[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]2)=[CH:6][C:3]=1[CH:4]=[O:5]

Participants

3

Reactant 2

HCID 137636Cyclohexane, (bromomethyl)-HCID 3871792-Bromo-5-hydroxybenzaldehyde

Product 1

HCID 815895652-Bromo-5-(cyclohexylmethoxy)benzaldehyde

Procedure

Alkylation of 2-bromo-5-hydroxybenzaldehyde using (bromomethyl)cyclohexane following the method used in Example 1 gave 2-bromo-5-(cyclohexylmethoxy)benzaldehyde. The crude aldehyde was used in the subsequent reaction.

Sources & evidence

ORD record
ord-ec8aa411a2cd4877aa28c6b7bbf3025e
Source dataset
uspto-grants-2015_03
Patent number
US08993807B2

Reaction notes

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