Benzyl Chloride → HCID 86678392, compound

HRID 882639Notes

Reaction equation

HRID 882639 reaction equation
[OH:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][O:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14].[CH2:16](Cl)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.C(=O)([O-])[O-].[Cs+].[Cs+]>>[O:1]=[CH:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH2:8][CH2:9][O:10][CH2:11][CH2:12][C:13]([O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:14]

Participants

4

Reactant 3

HCID 7503Benzyl ChlorideHCID 10796Cesium carbonateHCID 21880732HCID 21880732, compound

Product 1

HCID 86678392HCID 86678392, compound

Procedure

The title compound was prepared from 6 g (21.55 mmol) of commercially available 3-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}propanoic acid under standard conditions, first by esterification with benzyl chloride and caesium carbonate and subsequent oxidation with sulphur trioxide-pyridine complex.

Sources & evidence

ORD record
ord-f8e4bcdbd64e43ef9be6219ffef8df38
Source dataset
uspto-grants-2015_03
Patent number
US08992932B2

Reaction notes

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