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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 882705Generated: October 27, 2026

p-Toluenesulfonic acid → (5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione tosylate

https://huagongshe.com/reaction/882705

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Toluenesulfonic acidHCID 6101—
Reactant(5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione (-)-O,O'-dibenzoyl-L-tartrateHCID 53343681—
SolventIsopropanolHCID 3776—
Product(5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione tosylateHCID 86651734—

Reaction Steps

To a solution of p-toluenesulphonic acid (0.8 g) in IPA (12 mL) at 40° C. was added (5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione (−)-O,O′-dibenzoyl-L-tartrate

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236786B2
Source datasetuspto-grants-2012_08
ORD IDord-7d7a30e5301d4af198e645938ca0c996
Source noteuspto-grants-2012_08