HCID 67442555, compound → HCID 67441600, compound

HRID 882725Notes

Reaction equation

HRID 882725 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH:16]3[CH2:17][CH2:18][N:13]([CH2:14][CH2:15]3)[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-])=O>[Pd].CO>[N:13]12[CH2:18][CH2:17][CH:16]([CH2:15][CH2:14]1)[N:10]([C:7]1[CH:8]=[CH:9][C:4]([NH2:1])=[CH:5][CH:6]=1)[CH2:11][CH2:12]2

Participants

4

Reactant 1

HCID 67442555HCID 67442555, compound

Product 1

HCID 67441600HCID 67441600, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of 4-(4-nitro-phenyl)-1,4-diaza-bicyclo[3.2.2]nonane (0.50 g, 2.0 mmol), palladium on carbon (100 mg, 10%) and methanol (60 ml) was stirred for 15 minutes under hydrogen (130 ml of hydrogen was consumed). The crude mixture was filtered through celite and the product was isolated as an oil in quantitative yield.

Workup

  1. filtrationThe crude mixture was filtered through celite
  2. customthe product was isolated as an oil in quantitative yield

Sources & evidence

ORD record
ord-c1709d257dda4d9eb5ef3dd5beeeef5d
Source dataset
uspto-grants-2012_08
Patent number
US08236793B2

Reaction notes

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