HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitrate(1-), oxo- → N-(4-Amino-3,4-dioxo-1-phenylbutan-2-yl)-1-benzyl-6-oxo-1,6-dihydropyridine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitrate(1-), oxo- | HCID 3001380 | — |
| Reactant | 3-Amino-2-hydroxy-4-phenylbutanamide | HCID 13882355 | — |
| Reactant | 1-Benzyl-6-oxo-1,6-dihydropyridine-2-carboxylic acid | HCID 66644812 | — |
| Reactant | HCID 178514248 | HCID 178514248 | — |
| Product | N-(4-Amino-3,4-dioxo-1-phenylbutan-2-yl)-1-benzyl-6-oxo-1,6-dihydropyridine-2-carboxamide | HCID 49785938 | — |
Reaction Steps
Coupling of 1-benzyl-6-oxo-1,6-dihydro-pyridine-2-carboxylic acid with 3-amino-2-hydroxy-4-phenylbutanamide and oxidation of the resulting hydroxyamide intermediate to the corresponding ketoamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08236798B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-06827dd01a3943faa74b440c4ab4c050 |
| Source note | uspto-grants-2012_08 |