Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 882826Generated: October 27, 2026

Nitrate(1-), oxo- → HCID 67095120, compound

https://huagongshe.com/reaction/882826

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitrate(1-), oxo-HCID 3001380—
Reactant3-Amino-2-hydroxy-4-phenylbutanamideHCID 13882355—
Reactant1-[(4-Fluorophenyl)methyl]-5-oxo-D-prolineHCID 40516921—
ReactantHCID 178514248HCID 178514248—
ProductHCID 67095120HCID 67095120—

Reaction Steps

Coupling of (R)-1-(4-fluoro-benzyl)-5-oxo-pyrrolidine-2-carboxylic acid with 3-amino-2-hydroxy-4-phenylbutanamide and oxidation of the resulting hydroxyamide intermediate to the corresponding ketoamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236798B2
Source datasetuspto-grants-2012_08
ORD IDord-d989a2054b854842a7ad3c3e128beb4e
Source noteuspto-grants-2012_08