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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 882860Generated: October 25, 2026

2-Thiopheneglyoxylic acid → 7-methoxy-3-thiophen-2-yl-1H-quinoxalin-2-one

https://huagongshe.com/reaction/882860

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneglyoxylic acidHCID 77694—
Reactant4-Methoxy-o-phenylenediamineHCID 153404—
Product7-methoxy-3-thiophen-2-yl-1H-quinoxalin-2-oneHCID 21083674—

Reaction Steps

The quinoxalin-2-one of the present example is prepared with 4-Methoxy-benzene-1,2-diamine and (thiophen-2-yl)oxo-acetic acid via the method described in Example 12 to afford 7-Methoxy-3-thiophen-2-yl-1H-quinoxalin-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236807B2
Source datasetuspto-grants-2012_08
ORD IDord-dbf37f3d00b440c8a5e53710419fc8bf
Source noteuspto-grants-2012_08