HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(4-Bromobutyl)phthalimide → (4-Amino-butyl)-{2-[(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-amino]-ethyl}-dimethyl-ammonium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(4-Bromobutyl)phthalimide | HCID 93575 | — |
| Reactant | (2-Amino-ethyl)-{2-[(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-amino]-ethyl}-dimethyl-ammonium bromide | HCID 86656647 | — |
| Product | (4-Amino-butyl)-{2-[(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-amino]-ethyl}-dimethyl-ammonium bromide | HCID 86656640 | — |
Reaction Steps
The title compound is prepared by an analogous procedure to (2-amino-ethyl)-{2-[(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-amino]-ethyl}-dimethyl-ammonium bromide (Intermediate K) by replacing N-(4-bromoethyl)-phthalimide with N-(4-bromobutyl)-phthalimide. M+ 330.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08236808B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-e17217b545f241589a8b5aed02ec202e |
| Source note | uspto-grants-2012_08 |