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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 882933Generated: October 30, 2026

N-(4-Bromopentyl)phthalimide → (5-Amino-pentyl)-{2-[(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-amino]-ethyl}-dimethyl-ammonium bromide

https://huagongshe.com/reaction/882933

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(4-Bromopentyl)phthalimideHCID 240534—
Reactant(2-Amino-ethyl)-{2-[(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-amino]-ethyl}-dimethyl-ammonium bromideHCID 86656647—
Product(5-Amino-pentyl)-{2-[(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-amino]-ethyl}-dimethyl-ammonium bromideHCID 86656644—

Reaction Steps

The title compound is prepared by an analogous procedure to (2-amino-ethyl)-{2-[(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-amino]-ethyl}-dimethyl-ammonium bromide (Intermediate K) by replacing N-(4-bromoethyl)-phthalimide with N-(4-bromopentyl)-phthalimide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236808B2
Source datasetuspto-grants-2012_08
ORD IDord-2f282106cbcf4cf1b6ecc9f3820404a7
Source noteuspto-grants-2012_08