HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) → 1-Ethyl-4,4,6-trimethyl-7-(2-trifluoromethoxy-phenyl)-3,4-dihydro-1H-quinolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) | HCID 2777204 | — |
| Reactant | 7-Bromo-1-ethyl-4,4,6-trimethyl-3,4-dihydro-1H-quinolin-2-one | HCID 21966486 | — |
| Product | 1-Ethyl-4,4,6-trimethyl-7-(2-trifluoromethoxy-phenyl)-3,4-dihydro-1H-quinolin-2-one | HCID 68666393 | — |
Reaction Steps
Compound 9A was prepared from Compound 1A using the procedure described in Example 1B, except using 2-trifluoromethoxy benzene boronic acid as the starting material. MS (electrospray): mass calculated for C21H22F3NO2 377.16; m/z found m/z found, 378.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08236819B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-d90a840a2dbc425bab429a7f289f65f6 |
| Source note | uspto-grants-2012_08 |