Lawesson's reagent → HCID 24809546, compound

Participants

Reaction Steps

Compound 2 (60.0 mg, 0.160 mmol) obtained in Example 2 was dissolved in DME (1.0 mL). To this was added Lawesson's reagent (71.0 mg, 0.170 mmol), and then the mixture was stirred under ref lux for 1 hour. The solvent was evaporated off in vacuo and the residue was purified by column chromatography (hexane/ethyl acetate=50/50). The resulting crude crystals were reslurried with hexane to give the title compound (40.0 mg, 0.100 mmol, yield 65%).

Provenance & Evidence