HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl cyanoacetate → HCID 67424997, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl cyanoacetate | HCID 7747 | — |
| Reactant | 6-Chloroindoline-2,3-dione | HCID 241331 | — |
| Product | HCID 67424997 | HCID 67424997 | 84% |
Reaction Steps
Following the general method as outlined for Intermediate 1, starting from 6-chloro isatin and methyl cyanoacetate, the title compound was isolated, after evaporation, as a dark brown solid in 84% yield. This was a 5.5:1 mixture of geometric isomers (98% purity by HPLC).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08236963B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-e7103080cd07456797883e0f06deca2e |
| Source note | uspto-grants-2012_08 |