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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 883765Generated: October 25, 2026

Benzonitrile, 4-bromo- → 1-Boc-4-[(4-cyanophenyl)amino]-piperidine

https://huagongshe.com/reaction/883765

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzonitrile, 4-bromo-HCID 12162—
Reactant4-Amino-1-Boc-piperidineHCID 1268291—
Reactant1,1-Dimethylethyl 4-[(3-cyanophenyl)amino]-1-piperidinecarboxylateHCID 25223796—
Product1-Boc-4-[(4-cyanophenyl)amino]-piperidineHCID 18539207—

Reaction Steps

The title compound was prepared from 1,1-dimethylethyl 4-amino-1-piperidinecarboxylate and 4-bromobenzonitrile using a method similar to that described for D5 in Description 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236953B2
Source datasetuspto-grants-2012_08
ORD IDord-bee17b41bf9a4de2be645ca05b96cb90
Source noteuspto-grants-2012_08