Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 883772Generated: October 27, 2026

N-(3-fluorophenyl)piperidin-4-amine → N-(2-fluorophenyl)piperidin-4-amine

https://huagongshe.com/reaction/883772

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-fluorophenyl)piperidin-4-amineHCID 4778195—
ReactantTert-butyl 4-[(2-fluorophenyl)amino]piperidine-1-carboxylateHCID 43652152—
ProductN-(2-fluorophenyl)piperidin-4-amineHCID 4778194—

Reaction Steps

The title compound was prepared from 1,1-dimethylethyl 4-[(2-fluorophenyl)amino]-1-piperidinecarboxylate (D15) using a method similar to that described for D4 in Description 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236953B2
Source datasetuspto-grants-2012_08
ORD IDord-d632acd1bb104aba9a4727d6679d7463
Source noteuspto-grants-2012_08