Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 883773Generated: October 26, 2026

2-Bromobenzonitrile → 1,1-Dimethylethyl 4-[(2-cyanophenyl)amino]-1-piperidinecarboxylate

https://huagongshe.com/reaction/883773

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-BromobenzonitrileHCID 16272—
Reactant4-Amino-1-Boc-piperidineHCID 1268291—
Reactant1,1-Dimethylethyl 4-[(3-cyanophenyl)amino]-1-piperidinecarboxylateHCID 25223796—
Product1,1-Dimethylethyl 4-[(2-cyanophenyl)amino]-1-piperidinecarboxylateHCID 57699512—

Reaction Steps

The title compound was prepared from 1,1-dimethylethyl 4-amino-1-piperidinecarboxylate and 2-bromobenzonitrile using a method similar to that described for D5 in Description 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236953B2
Source datasetuspto-grants-2012_08
ORD IDord-de010a6f56cf47cf92fb2aad06c0cdd6
Source noteuspto-grants-2012_08