1-Butanol → 1,3-Propanediol

HRID 883814Notes

Reaction equation

HRID 883814 reaction equation
[OH:1][CH2:2][CH:3]([CH2:5][OH:6])[OH:4].C([OH:9])C.[CH2:10]([OH:14])[CH2:11][CH2:12][CH3:13]>>[CH2:5]([OH:6])[CH2:3][CH2:2][OH:1].[C:10]([OH:9])(=[O:14])[CH2:11][CH2:12][CH3:13].[C:10]([OH:1])(=[O:14])[CH2:11][CH2:12][CH3:13].[C:5]([OH:6])(=[O:9])[CH:3]([CH3:2])[OH:4].[C:5]([OH:6])(=[O:9])[CH:3]([CH3:2])[OH:4]

Participants

6

Reactant 3

HCID 2631-ButanolHCID 702EthanolHCID 753Glycerol

Product 3

HCID 104421,3-PropanediolHCID 87075455HCID 87075455, compoundHCID 87184772HCID 87184772, compound

Procedure

Both natural and recombinant clostridia produce 1,3-propanediol at a maximal yield of 0.55 g/g of glycerol due to the co-production of reduced compounds like butyric acid (butyrate), lactic acid (lactate), ethanol or butanol. To increase the yield of 1,3-propanediol production it is necessary to avoid the production of all the reduced co-products and associate the production of 1,3-propanediol to an oxidized co-product.

Sources & evidence

ORD record
ord-248fc8f4dec648c988202b5e48753fea
Source dataset
uspto-grants-2012_08
Patent number
US08236994B2

Reaction notes

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