Stannous Chloride → 5-Methyl-2-phenylsulfanyl-phenylamine

関与物質

反応手順

A solution of the product from Example 7e (1.17 g, 7.0 mmol) in 25 mL of absolute EtOH and SnCl2 (3.58 g, 29.8 mmol) was stirred at room temperature for 16 h. Adjusted to pH 12 with 1N NaOH and extracted with EtOAc. Dried over Na2SO4, filtered and concentrated under vacuum giving the title compound (835 mg, 82%) 1H NMR (300 MHz, CDCl3) δ ppm: 2.30 (2, 3 H) 6.62 (d, J=8.83 Hz, 1 H) 6.69 (s, 1 H) 7.10 (m, 3 H) 7.21 (m, 2 H) 7.54 (d, J=7.72 Hz, 2 H).

情報源と証拠