HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl 2-((6-ethylpyridin-2-ylamino)methylene)malonate → Ethyl 7-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl 2-((6-ethylpyridin-2-ylamino)methylene)malonate | HCID 12354398 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | Ethyl 7-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate | HCID 12354420 | 80% |
Reaction Steps
The product of Example 8c (7.16 g, 0.024 mol) was heated in diphenyl ether following the procedure in Example 7b giving the title compound (4.73 g, 79%) as a tan solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08236950B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-ff726582d819408680e736186e326802 |
| Source note | uspto-grants-2012_08 |