4-Chloro-3-nitrophenol → HCID 60204756, compound

HRID 883918Notes

Reaction equation

HRID 883918 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].Br.Br[CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=2)=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 691274-Chloro-3-nitrophenolHCID 27347202-(Bromomethyl)pyridine hydrobromide

Product 1

HCID 60204756HCID 60204756, compound

Procedure

A solution of 4-chloro-3-nitro-phenol was reacted with 2-Bromomethyl-pyridine hydrobromide salt using the conditions described in Example 10C to provide 2-(4-Chloro-3-nitro-phenoxymethyl)-pyridine which was treated sequentially using the procedures from Examples 10D and 10E to provide the title product.

Sources & evidence

ORD record
ord-0c762bbed6304fd483c535f4cb811f8e
Source dataset
uspto-grants-2012_08
Patent number
US08236950B2

Reaction notes

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