4-Chloro-3-nitrophenol → HCID 60204759, compound

HRID 883919Notes

Reaction equation

HRID 883919 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].Br[CH2:13][C:14]1[CH:21]=[CH:20][CH:19]=[CH:18][C:15]=1[C:16]#[N:17]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:13][C:14]2[CH:21]=[CH:20][CH:19]=[CH:18][C:15]=2[C:16]#[N:17])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10]

Participants

3

Reactant 2

HCID 691274-Chloro-3-nitrophenolHCID 895992-(Bromomethyl)benzonitrile

Product 1

HCID 60204759HCID 60204759, compound

Procedure

A solution of 4-chloro-3-nitro-phenol was reacted with 2-Bromomethyl-benzonitrile using the conditions described in Example 10C to provide 2-(4-Chloro-3-nitro-phenoxymethyl)-benzonitrile which was treated sequentially using the procedures from Examples 10D and 10E to provide the title product.

Sources & evidence

ORD record
ord-215af449b6274c8abb62e9a2a5b726be
Source dataset
uspto-grants-2012_08
Patent number
US08236950B2

Reaction notes

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