HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → 3-Amino-4-(4-hydroxy-phenylsulfanyl)-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 4-(4-Hydroxy-phenylsulfanyl)-3-nitro-phenol | HCID 67040361 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Amino-4-(4-hydroxy-phenylsulfanyl)-phenol | HCID 67040301 | 98.4% |
Reaction Steps
The product from Example 48A (1.34 g, 5.09 mmol) was reacted with iron (1.42 g, 25.48 mmol) and ammonium chloride (409 mg, 1.5 mmol) in 20 mL EtOH/20 ml, THF/6 mL water following the procedure from Example 10E to provide the title compound (1.168 g, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08236950B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-96ffba23fe7243768eedc6596809cbeb |
| Source note | uspto-grants-2012_08 |