HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Methoxy-phenyl)-vinyl-4-methyl-2-nitro-benzene → 2-[2-(4-Methoxy-phenyl)-ethyl]-5-methyl-phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Methoxy-phenyl)-vinyl-4-methyl-2-nitro-benzene | HCID 86614623 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-[2-(4-Methoxy-phenyl)-ethyl]-5-methyl-phenylamine | HCID 66808269 | 97% |
Reaction Steps
To a solution of the product from Example 75A (164 mg, 0.6 mmol) and 10% palladium on charcoal (50 mg) in ethanol (20 ml) was hydrogenated with a hydrogen balloon for three days. The solvent was filtered through celite, washed with ethanol and evaporated under vacuum to provide the title compound (140 mg, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08236950B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-87e720e459d64483927b210a1ea82639 |
| Source note | uspto-grants-2012_08 |