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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 883973Generated: October 27, 2026

2-(4-Methoxy-phenyl)-vinyl-4-methyl-2-nitro-benzene → 2-[2-(4-Methoxy-phenyl)-ethyl]-5-methyl-phenylamine

https://huagongshe.com/reaction/883973

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Methoxy-phenyl)-vinyl-4-methyl-2-nitro-benzeneHCID 86614623—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product2-[2-(4-Methoxy-phenyl)-ethyl]-5-methyl-phenylamineHCID 6680826997%

Reaction Steps

To a solution of the product from Example 75A (164 mg, 0.6 mmol) and 10% palladium on charcoal (50 mg) in ethanol (20 ml) was hydrogenated with a hydrogen balloon for three days. The solvent was filtered through celite, washed with ethanol and evaporated under vacuum to provide the title compound (140 mg, 97%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236950B2
Source datasetuspto-grants-2012_08
ORD IDord-87e720e459d64483927b210a1ea82639
Source noteuspto-grants-2012_08