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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 884118Generated: November 1, 2026

HCID 68522204, compound → HCID 68525767, compound

https://huagongshe.com/reaction/884118

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68522204HCID 68522204—
CatalystHCID 178418390HCID 178418390—
SolventEthanol ethylacetateHCID 21584252—
ProductHCID 68525767HCID 6852576794%

Reaction Steps

To a solution of ethyl 3-(4-{5[benzyloxycarbonyl(2-methoxyethyl)amino]pyridin-2-yloxy}phenyl}propionate (1.82 g, 3.8 mmol) in ethanol-ethyl acetate (10 mL-10 mL) was added under a nitrogen atmosphere 10% palladium-carbon (0.2 g), and the resulting solution was stirred for 3 hours under a hydrogen atmosphere at atmospheric pressure. The palladium-carbon was filtered off through Celite, and the filtrate was evaporated to yield 1.23 g of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236826B2
Source datasetuspto-grants-2012_08
ORD IDord-2854965e2fa544fa8836a377dba187ab
Source noteuspto-grants-2012_08