HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68522204, compound → HCID 68525767, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68522204 | HCID 68522204 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol ethylacetate | HCID 21584252 | — |
| Product | HCID 68525767 | HCID 68525767 | 94% |
Reaction Steps
To a solution of ethyl 3-(4-{5[benzyloxycarbonyl(2-methoxyethyl)amino]pyridin-2-yloxy}phenyl}propionate (1.82 g, 3.8 mmol) in ethanol-ethyl acetate (10 mL-10 mL) was added under a nitrogen atmosphere 10% palladium-carbon (0.2 g), and the resulting solution was stirred for 3 hours under a hydrogen atmosphere at atmospheric pressure. The palladium-carbon was filtered off through Celite, and the filtrate was evaporated to yield 1.23 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08236826B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-2854965e2fa544fa8836a377dba187ab |
| Source note | uspto-grants-2012_08 |