HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 88425Generated: October 30, 2026
Dimethylformamide → 1-[(4-aminoquinazolin-7-yl)methyl]-4-[3-(5-chlorothiophen-2-yl)prop-2-enoyl]-3,5-dimethylpiperazin-2-one
https://huagongshe.com/reaction/88425
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Tetrafluoroborate | HCID 26255 | — |
| Reactant | O-benzotriazol-1-yl-tetramethyluronium | HCID 130500 | — |
| Reactant | 1-[(4-Aminoquinazolin-7-yl)methyl]-3,5-dimethylpiperazin-2-one | HCID 17985172 | — |
| Reactant | 3-(5-Chlorothiophen-2-yl)prop-2-enoic acid | HCID 53401827 | — |
| Product | 1-[(4-aminoquinazolin-7-yl)methyl]-4-[3-(5-chlorothiophen-2-yl)prop-2-enoyl]-3,5-dimethylpiperazin-2-one | HCID 178430233 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (2/10) |
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| ORD ID | ord-b14b16981ad94d4b829d56513189d805 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (2/10) |
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