HuagongsheHuagongshe Chemistry Print Report · For research reference only
Spermine → (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Spermine | HCID 1103 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Geraniol | HCID 637566 | — |
| Reactant | Sodium Laurate | HCID 2735067 | — |
| Reactant | (5xi)-1,4-Anhydro-6-O-hexadecanoyl-D-xylo-hexitol | HCID 70687305 | — |
| Solvent | 1-Octanol | HCID 957 | — |
| Product | (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal | HCID 107526 | — |
Reaction Steps
A composition was prepared by dissolving human insulin with spermine and polyvinylpyrrolidone (PVP-40), sodium dodecanoate (SD) and methylcellulose (MC-400) in DDW containing NaOH. The solution was then lyophilized and suspended with octanol and geraniol in a mixture of medium chain triglyceride (MCT) oil and castor oil, further containing sorbitan monopalmitate (Span-40). Components and concentrations are detailed in Table 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08241670B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-45a82a040f7f4059a8c318bef89ed52d |
| Source note | uspto-grants-2012_08 |