2,5-Dichloropyrimidine → HCID 44512032, compound

Participants

Reaction Steps

The title compound was prepared following a procedure analogous to that described in Example 1 using (S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-pyrrolidin-3-yl)-1,3-oxazinan-2-one and 2,5-dichloropyrimidine at 150° C. for 20 min. LC-MS Method 1 tR=1.51 min, m/z=431,433(M+1); 1H NMR (CD3OD) 8.24(s, 2H), 7.41-7.27(m, 5H), 4.78(m, 1H), 3.71-3.57(m, 2H), 2.73(m, 1H), 2.52(m, 2H), 2.17(s, 2H), 1.24(s, 3H), 0.93(s, 3H).

Provenance & Evidence