HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxy-4-morpholin-4-yl-benzaldehyde → 1-(2-Hydroxy-4-morpholin-4-yl-phenyl)-propan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxy-4-morpholin-4-yl-benzaldehyde | HCID 9815659 | — |
| Reactant | HCID 178418443 | HCID 178418443 | — |
| Product | 1-(2-Hydroxy-4-morpholin-4-yl-phenyl)-propan-1-one | HCID 9964689 | — |
Reaction Steps
Following the procedure for preparing Example 34, 4-(4-morpholinyl)salicylaldehyde (1.0 g, 5 mmol) and ethylmagnesium bromide (1.0 M solution in tetrahydrofuran, 11 mL, 11 mmol) were converted to the product (208 mg, 18%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242115B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-1425beda84544475abdad9e938453657 |
| Source note | uspto-grants-2012_08 |