HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxy-4-morpholin-4-yl-benzaldehyde → DNA-PK inhibitor V
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxy-4-morpholin-4-yl-benzaldehyde | HCID 9815659 | — |
| Reactant | HCID 178506676 | HCID 178506676 | — |
| Product | DNA-PK inhibitor V | HCID 16760391 | — |
Reaction Steps
Following the procedure for preparing Example 34, 4-(4-morpholinyl)-salicylaldehyde (1.0 g, 5 mmol) and phenyllithium (1.8 M solution in tetrahydrofuran, 6.0 mL, 11 mmol) were converted to the product (387 mg, 28%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242115B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-2d365876f6c7407caf49018125ac585d |
| Source note | uspto-grants-2012_08 |