HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → Methyl 2-amino-5-(2,2-difluoroethoxy)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Methyl 5-(2,2-difluoroethoxy)-2-nitrobenzoate | HCID 59587324 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl 2-amino-5-(2,2-difluoroethoxy)benzoate | HCID 59587097 | — |
Reaction Steps
21 g of methyl 5-(2,2-difluoroethoxy)-2-nitrobenzoate obtained in stage 3.1 and 1 g of Pd/C (10%) in a mixture of 300 ml of AcOEt, 50 ml of EtOH and 5 ml of AcOH are stirred at AT under a hydrogen atmosphere for 24 h 00.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242126B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-67749a367e244925b95db98052abf859 |
| Source note | uspto-grants-2012_08 |