Ethanol → Ethyl (3-Hydroxyphenyl)acetate
Reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH2:8][C:9]([OH:11])=[O:10])[CH:5]=[CH:6][CH:7]=1.S(=O)(=O)(O)O.[CH3:17][CH2:18]O>>[CH2:17]([O:10][C:9](=[O:11])[CH2:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([OH:1])[CH:3]=1)[CH3:18]Participants
4
Procedure
3-Hydroxyphenylacetic acid (5.0 g, 32.9 mmol) and sulfuric acid (1 mL) in EtOH (100 mL) were heated to 70° C. for 1 hour. After work-up, 5.2 g of the desired product was obtained.
Sources & evidence
- ORD record
- ord-ba937eb0ea7f4aeab95dcc9c91631bca
- Source dataset
- uspto-grants-2012_08
- Patent number
- US08242145B2
Reaction notes
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