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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885242Generated: October 31, 2026

Lithium Hydroxide → {3-[4-Methyl-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-phenyl}-acetic acid

https://huagongshe.com/reaction/885242

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant{3-[4-Methyl-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-phenyl}-acetic acid ethyl esterHCID 58237553—
SolventMethanolHCID 887—
SolventWaterHCID 962—
Product{3-[4-Methyl-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-phenyl}-acetic acidHCID 44187531—

Reaction Steps

Hydrolysis of {3-[4-methyl-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-phenyl}-acetic acid ethyl ester with lithium hydroxide in MeOH and H2O at 60° C. provided the desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242145B2
Source datasetuspto-grants-2012_08
ORD IDord-9ea0ecb008704cab8402b86480ab1794
Source noteuspto-grants-2012_08