2-Fluoro-5-(trifluoromethyl)benzaldehyde → HCID 58237661, compound
Reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:8]([CH3:13])([CH3:12])[C:9]([OH:11])=[O:10])[CH:5]=[CH:6][CH:7]=1.F[C:15]1[CH:22]=[CH:21][C:20]([C:23]([F:26])([F:25])[F:24])=[CH:19][C:16]=1[CH:17]=[O:18]>>[CH:17]([C:16]1[CH:19]=[C:20]([C:23]([F:24])([F:25])[F:26])[CH:21]=[CH:22][C:15]=1[O:1][C:2]1[CH:3]=[C:4]([C:8]([CH3:13])([CH3:12])[C:9]([OH:11])=[O:10])[CH:5]=[CH:6][CH:7]=1)=[O:18]Participants
3
Procedure
Prepared according to the procedure described in Example 10, Step 4, using the following starting materials: 2-(3-hydroxy-phenyl)-2-methyl-propionic acid and 2-fluoro-5-(trifluoromethyl)benzaldehyde.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-eb7d8ed2b49045aebc93a714846dfbd4
- Source dataset
- uspto-grants-2012_08
- Patent number
- US08242145B2
Reaction notes
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