[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]acetic acid methyl ester → HCID 58237436, compound

HRID 885276Notes

Reaction equation

HRID 885276 reaction equation
[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([Br:18])=[CH:14][C:13]=2[CH2:19]Br)[CH:6]=1.[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([C@H:29]2[O:33][C:32](=[O:34])[NH:31][C@H:30]2[CH3:35])=[CH:25][CH:24]=1>>[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([Br:18])=[CH:14][C:13]=2[CH2:19][N:31]2[C@@H:30]([CH3:35])[C@@H:29]([C:26]3[CH:25]=[CH:24][C:23]([Cl:22])=[CH:28][CH:27]=3)[O:33][C:32]2=[O:34])[CH:6]=1

Participants

3

Reactant 2

HCID 58237479[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]acetic acid methyl esterHCID 58237520HCID 58237520, compound

Product 1

HCID 58237436HCID 58237436, compound

Procedure

Prepared according to the procedure described in Example 6, Step 5, using the following starting materials: [3-(4-bromo-2-bromomethyl-phenoxy)-phenyl]acetic acid methyl ester and (4S,5R)-5-(4-chloro-phenyl)-4-methyl-oxazolidin-2-one.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-02e378570b0b4fcb92b5286c56d452b7
Source dataset
uspto-grants-2012_08
Patent number
US08242145B2

Reaction notes

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