[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]acetic acid methyl ester → HCID 58237528, compound

HRID 885278Notes

Reaction equation

HRID 885278 reaction equation
[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([Br:18])=[CH:14][C:13]=2[CH2:19]Br)[CH:6]=1.[F:22][C:23]1[CH:24]=[C:25]([C@H:30]2[O:34][C:33](=[O:35])[NH:32][C@H:31]2[CH3:36])[CH:26]=[C:27]([F:29])[CH:28]=1>>[CH3:1][O:2][C:3](=[O:21])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([Br:18])=[CH:14][C:13]=2[CH2:19][N:32]2[C@@H:31]([CH3:36])[C@@H:30]([C:25]3[CH:24]=[C:23]([F:22])[CH:28]=[C:27]([F:29])[CH:26]=3)[O:34][C:33]2=[O:35])[CH:6]=1

Participants

3

Reactant 2

HCID 58237479[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]acetic acid methyl esterHCID 58237480HCID 58237480, compound

Product 1

HCID 58237528HCID 58237528, compound

Procedure

Prepared according to the procedure described in Example 6, Step 5, using the following starting materials: [3-(4-bromo-2-bromomethyl-phenoxy)-phenyl]-acetic acid methyl ester and (4S,5R)-5-(3,5-difluoro-phenyl)-4-methyl-oxazolidin-2-one.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-9d09ce52e0f5481d88ccb936287da1b8
Source dataset
uspto-grants-2012_08
Patent number
US08242145B2

Reaction notes

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