Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885279Generated: October 27, 2026

1-Bromo-3,5-bis(trifluoromethyl)benzene → benzyl {(1S)-2-[3,5-bis(trifluoromethyl)phenyl]-1-methyl-2-oxoethyl}carbamate

https://huagongshe.com/reaction/885279

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3,5-bis(trifluoromethyl)benzeneHCID 67602—
Reactant(S)-Benzyl 1-(methoxy(methyl)amino)-1-oxopropan-2-ylcarbamateHCID 10515879—
Productbenzyl {(1S)-2-[3,5-bis(trifluoromethyl)phenyl]-1-methyl-2-oxoethyl}carbamateHCID 11589807—

Reaction Steps

Prepared according to the procedure described in Example 16, Step 2, using the following starting materials: [(S)-1-(methoxy-methyl-carbamoyl)-ethyl]-carbamic acid benzyl ester and 3,5-bis(trifluoromethyl)bromobenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242145B2
Source datasetuspto-grants-2012_08
ORD IDord-4dd53538b6df40dfbe3a706e19016f83
Source noteuspto-grants-2012_08