HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → (5-Benzyloxy-2-chloro-phenyl)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | (5-Benzyloxy-2-chloro-phenyl)-acetic acid | HCID 58149280 | — |
| Product | (5-Benzyloxy-2-chloro-phenyl)-acetic acid ethyl ester | HCID 58148945 | — |
Reaction Steps
To (5-benzyloxy-2-chloro-phenyl)-acetic acid (1.5 g, 5.4 mmol) in EtOH (30 mL) was added sulfuric acid (1 mL), and the mixture was stirred overnight at room temperature. Once no starting material was seen by analytical LCMS, the reaction was worked up to give the desired product (1.7 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242145B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-4ea0a002f821468680f898a07d33da0e |
| Source note | uspto-grants-2012_08 |