4-Methyl-5-phenyl-2-oxazolidinone, (4S,5R)- → HCID 58237484, compound

HRID 885303Notes

Reaction equation

HRID 885303 reaction equation
[CH2:1]([O:3][C:4](=[O:26])[CH2:5][C:6]1[CH:11]=[C:10]([C:12]([F:15])([F:14])[F:13])[CH:9]=[C:8]([O:16][C:17]2[CH:22]=[CH:21][C:20]([Br:23])=[CH:19][C:18]=2[CH2:24]Br)[CH:7]=1)[CH3:2].[CH3:27][C@H:28]1[C@@H:32]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[O:31][C:30](=[O:39])[NH:29]1>>[CH2:1]([O:3][C:4](=[O:26])[CH2:5][C:6]1[CH:11]=[C:10]([C:12]([F:14])([F:15])[F:13])[CH:9]=[C:8]([O:16][C:17]2[CH:22]=[CH:21][C:20]([Br:23])=[CH:19][C:18]=2[CH2:24][N:29]2[C@@H:28]([CH3:27])[C@@H:32]([C:33]3[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=3)[O:31][C:30]2=[O:39])[CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 8531614-Methyl-5-phenyl-2-oxazolidinone, (4S,5R)-HCID 58237551HCID 58237551, compound

Product 1

HCID 58237484HCID 58237484, compound

Procedure

Prepared according to the procedure described in Example 24, Step 7, using the following starting materials: [3-(4-bromo-2-bromomethyl-phenoxy)-5-trifluoromethyl-phenyl]-acetic acid ethyl ester and (4S,5R)-(−)-4-methyl-5-phenyl-2-oxazolidinone.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2ab3f389e7f04c6a84940420453c2eb4
Source dataset
uspto-grants-2012_08
Patent number
US08242145B2

Reaction notes

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