5-Bromo-2-fluorobenzaldehyde → HCID 58237473, compound
Reaction equation
[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]([OH:13])[CH:7]=1)[CH3:2].[Br:15][C:16]1[CH:17]=[CH:18][C:19](F)=[C:20]([CH:23]=1)[CH:21]=[O:22]>>[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]([O:13][C:19]2[CH:18]=[CH:17][C:16]([Br:15])=[CH:23][C:20]=2[CH:21]=[O:22])[CH:7]=1)[CH3:2]Participants
3
Procedure
Prepared according to the procedure described in Example 24, Step 4, using the following starting materials: (4-chloro-3-hydroxy-phenyl)-acetic acid ethyl ester and 5-bromo-2-fluorobenzaldehyde.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-67b90a8abb0b40f4b876294b948b8103
- Source dataset
- uspto-grants-2012_08
- Patent number
- US08242145B2
Reaction notes
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