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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885309Generated: October 30, 2026

4-Methyl-5-phenyl-1,3-oxazolidin-2-one → {3-[4-Chloro-2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl ester

https://huagongshe.com/reaction/885309

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methyl-5-phenyl-1,3-oxazolidin-2-oneHCID 250174—
Reactant[3-(2-Bromomethyl-4-chloro-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl esterHCID 58237456—
Product{3-[4-Chloro-2-((4S,5R)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl esterHCID 58237598—

Reaction Steps

Prepared according to the procedure described in Example 24, Step 7, using the following starting materials: [3-(2-bromomethyl-4-chloro-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester and (4S,5R)-(+4-methyl-5-phenyl-2-oxazolidinone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242145B2
Source datasetuspto-grants-2012_08
ORD IDord-e6091a5da91a47b6b839f967053bc76d
Source noteuspto-grants-2012_08