4-Methyl-5-phenyl-2-oxazolidinone, (4S,5R)- → HCID 58237495, compound

HRID 885312Notes

Reaction equation

HRID 885312 reaction equation
[CH2:1]([O:3][C:4](=[O:27])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:16]=2[CH2:25]Br)[CH:7]=1)[CH3:2].[CH3:28][C@H:29]1[C@@H:33]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[O:32][C:31](=[O:40])[NH:30]1>>[CH2:1]([O:3][C:4](=[O:27])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]([F:24])([F:23])[F:22])=[CH:17][C:16]=2[CH2:25][N:30]2[C@@H:29]([CH3:28])[C@@H:33]([C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)[O:32][C:31]2=[O:40])[CH:7]=1)[CH3:2]

Participants

3

Reactant 2

HCID 8531614-Methyl-5-phenyl-2-oxazolidinone, (4S,5R)-HCID 58237660[3-(2-Bromomethyl-4-trifluoromethyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester

Product 1

HCID 58237495HCID 58237495, compound

Procedure

Prepared according to the procedure described in Example 10, Step 7, using the following starting materials: [3-(2-bromomethyl-4-trifluoromethyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester and (4S,5R)-(−)-4-methyl-5-phenyl-2-oxazolidinone.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f35aef9f42f44ad680e72ca1854f8c24
Source dataset
uspto-grants-2012_08
Patent number
US08242145B2

Reaction notes

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