5-Bromo-2-fluorobenzaldehyde → [3-(4-Bromo-2-formyl-phenoxy)-4-methoxy-phenyl]acetic acid methyl ester

HRID 885316Notes

Reaction equation

HRID 885316 reaction equation
[CH3:1][O:2][C:3](=[O:14])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([OH:13])[CH:6]=1.[Br:15][C:16]1[CH:17]=[CH:18][C:19](F)=[C:20]([CH:23]=1)[CH:21]=[O:22]>>[CH3:1][O:2][C:3](=[O:14])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([O:13][C:19]2[CH:18]=[CH:17][C:16]([Br:15])=[CH:23][C:20]=2[CH:21]=[O:22])[CH:6]=1

Participants

3

Reactant 2

HCID 7363275-Bromo-2-fluorobenzaldehydeHCID 10465267Methyl 3-hydroxy-4-methoxyphenylacetate

Product 1

HCID 58237628[3-(4-Bromo-2-formyl-phenoxy)-4-methoxy-phenyl]acetic acid methyl ester

Procedure

Prepared according to the procedure described in Example 6, Step 2, using the following starting materials: (3-hydroxy-4-methoxy-phenyl)-acetic acid methyl ester and 5-bromo-2-fluorobenzaldehyde.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-111e5225ca4f4f7c9b1f572e6d748d20
Source dataset
uspto-grants-2012_08
Patent number
US08242145B2

Reaction notes

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